Welcome to our mRNA Configurator section!
Click technology holds the promise to revolutionize the mRNA Technology in drug development for cancer treatment, vaccine discovery and enables tailored manufactured mRNA with superior quality.
Since 2022, baseclick is guiding provider in custom messenger in vitro mRNA synthesis and modification for research and clinical applications. Our team of experts transforms your mRNA design ranging from research tool to mRNA product development.
baseclick supplies diverse types of mRNA
- High quality products and services at competitive prices
- Custom tailored support to meet specific applications
- Wide variety of modification
- Affordable custom synthesis up to 10 mg scales of mRNA
LITERATURE
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning, J. Luo, M. Molbay, Y. Chen, et al. 2025, Nat Biotechnol.
https://doi.org/10.1038/s41587-024-02528-1
Chemoenzymatic Preparation of Functional Click-Labeled Messenger RNA, S. Croce et al., 2020, ChemBioChem, Vol. 21, p. 1641.
https://doi.org/10.1002/cbic.201900718
5-Ethynyluridine: a bio-orthogonal uridine variant for mRNA-based therapies and vaccines, S. Maassen et al., 2023, ChemBioChem, Vol. 24, p. e202200658.
https://doi.org/10.1002/cbic.202200658
Multiple covalent fluorescence labeling of eukaryotic mRNA at the poly(A) tail enhances translation and can be performed in living cells, L. Anhäuser et al., 2019, Nucleic Acids Research, Vol. 47, No. 7.
https://doi.org/10.1093/nar/gkz084
Multiplexed dendritic targeting of alpha calcium calmodulin-dependent protein kinase II, neurogranin, and activity-regulated cytoskeleton-associated protein RNAs by the A2 pathway, Y. Gao et al., 2008, Mol. Biol. Cell, 19, p. 2311–2327.
https://doi.org/10.1091/mbc.e07-09-0914
Dendritically localized transcripts are sorted into distinct ribonucleoprotein particles that display fast directional motility along dendrites of hippocampal neurons, F. Tübing et al., 2010 J. Neurosci., 30, p. 4160–4170.
https://doi.org/10.1523/JNEUROSCI.3537-09.2010
Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles, G.S Wilkie and I. Davis, 2001 Cell, 105, p. 209–219.
We offer different modifications of mRNA.
